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THIS IS ONE “ASIA” DESTINATION YOU DON’T NEED!

July 2, 2012

ASIA (AUTOIMMUNE (AUTO-INFLAMMATORY) SYNDROME INDUCED BY ADJUVANTS) EXCERPT FROM FORTHCOMING BOOK

Between the above “ASIA” and Phuket I’ll take the island destination any day where the only threat to your health is a hangover and sunburn. This syndrome assembles a spectrum of immune-mediated diseases triggered by an adjuvant stimulus. An adjuvant is a substance used to enhance or magnify an antigen-specific immune response. All modern vaccines contain adjuvants such as aluminum. There is now a growing fear that the common adjuvants used in vaccines are themselves a cause of numerous chronic debilitating diseases such as a new syndrome coined in 2010 by a French myopathologist called macrophagic myofasciitis (MMF). Recently muscle biopsy at injection sites of vaccinated patients with a constellation of symptoms such as severe fatigue and muscle/joint aches revealed nanoparticles of Al contained within the cytoplasm of macrophages a major immune cell type typically seen in inflammatory conditions.

Recently in 2010 researchers Y. Shoenfield et al have reviewed the current data supporting a common denominator in four seemingly unrelated conditions: siliconosis from breast implants and the like, Gulf war syndrome (GWS), the macrophagic myofasciitis syndrome (MMF) and post-vaccination phenomena. All were linked with previous exposure to an adjuvant. Furthermore, these four diseases share a similar complex of signs and symptoms which further support a common denominator.[1]

The use of medical adjuvants has become common practice and substances such as aluminum adjuvant are added to most human and animal vaccines, while the adjuvant silicone is extensively used for breast implants and cosmetic procedures. Furthermore, ‘hidden adjuvants’ such as infectious material or house molds have also been associated with different immune mediated conditions. Formerly, adjuvants were thought to pose little or no independent threat. Alas, studies of animal models and humans demonstrated the ability of some of them to inflict autoimmunity and immune-mediated diseases by themselves.[2]

Researchers have suggested that several other distinct diseases may be induced by vaccine adjuvants such as polymyalgia rheumatica in association with the flu vaccine, patients developing SLE following immunization with the human papilloma vaccine, and 93 American patients diagnosed with immune-mediated conditions following inoculation with hepatitis B vaccine. Even though different autoimmune diseases were diagnosed, many manifestations were common to all patients and 86% of them fulfilled the criteria for ASIA.[3]

In addition they review the association between pediatric vaccines and the various mechanisms of aluminum toxicity and Crohn’s disease. In a separate Shoenfeld article the use of adjuvants, ASIA, and the possible contribution of vaccines in the development of chronic fatigue syndrome is discussed.[4]

In the above study the authors mention that plenty of clinical data has been presented in support of an association between adjuvants and immune-mediated diseases but providing proof of causality has remained elusive. However, in this article two experimental models are portrayed, both of which prove the concept of autoimmunity induced by adjuvants. The authors conclude that this global view of ASIA probably represents only the tip of the iceberg. While encouraging physicians to report unusual vaccine related illnesses to obtain a better feel for the true prevalence of this disease. They feel that the role of adjuvants in the pathogenesis of immune-mediated diseases can no longer be ignored, and the medical community must look towards producing safer adjuvants.


[1] Shoenfeld Y, Agmon-Levin N. ‘ASIA’ – autoimmune/inflammatory syndrome induced by adjuvants.

J Autoimmun. 2011 Feb;36(1):4-8. Epub 2010 Aug 13.

[2] (http://lup.sagepub.com/content/21/2/118.full) ·  N Agmon-Levin Lupus February 2012 vol. 21 no. 2 118-120. 07/02/2012

[3] IBID

[4] H. Rosenblum, Y. Shoenfeld. Infectious Disease Clinics of North America
Volume 25, Issue 4 , Pages 851-863, December 2011

Enter your zip code here

June 19, 2012

IN RESEARCHING MY UPCOMING BOOK I FOUND THIS TIDBIT OF INFO:

CELL PHONES DISRUPT THE BLOOD BRAIN BARRIER

Cell phone radiation can also interrupt the brains defensive system by disabling the blood brain barrier (BBB) allowing it to leak. The BBB is one of the most elaborate and sophisticated systems in the human body. It is a specialized type of capillary that has evolved to protect the neural elements-your brain-from toxicities of all sorts while allowing nourishing molecules in and removing waste-and it has served us well. When it breaks down the capillaries become more porus to larger and more toxic molecules. At that point anything that is NOT supposed to be in the brain can gain access to it and cause severe damage, dying of neurons, or malfunction.

One of the most common causes of BBB disruption is hypoglycemia as in the chronically dieting soccer mom. Another way is through the use of cell phones. Now add a can or two of diet soda to the newly porous BBB and you have instant excitotoxin damage via NutraSweet’s ability to over-stimulate glutamate receptors within the entirety of the brain-all of the brain thanks to a leaking BBB. This is just one example of introducing stuff that’s not supposed to be in the brain without doing anything “unusual.”

One of the easiest ways scientists use to determine a breakdown in the BBB is to expose a lab rat to cell phone radiation, sacrifice the animal and look for albumin in the brain. Anywhere in the body that contains a semipermeable membrane such as the kidney or brain capillaries we see that it is designed to contain the plasma’s major osmotic proteins such as albumin within the blood stream proper. If we consistently leak albumen (in the urine) as can happen in kidney disease we eventually swell up like a balloon with edema. In other words when we see albumen in places It’s not supposed to be we should be concerned.

That’s exactly what Dr Leif Salford noticed when he demonstrated cell phone radiation can cause leaks in the BBB. In research published in June 2003, with lab rats a single two-hour exposure to a cell phone, just once during its lifetime, permanently damaged the blood-brain barrier and, on autopsy 50 days later, was found to have damaged or destroyed up to 2 percent of an animal’s brain cells, including cells in areas of the brain concerned with learning, memory and movement.[1] Learning, memory, and movement? Heck that’s Alzheimer’s disease and Parkinson’s disease is it not?

Bottom line just two minutes of cell phone exposure causes BBB leaking and two hours causes permanent brain damage.

We’ve known that microwave radiation causes leaks ion the BBB for years. America’s Allan Frey, during the 1970s, was the first of many to demonstrate that low-level microwave radiation damages the blood-brain barrier. Similar mechanisms protect the eye (the blood-vitreous barrier) and the fetus (the placental barrier), and the work of Frey and others indicates that microwave radiation damages those barriers also. The implication: No pregnant woman should ever be using a cell phone.[2] There is also a blood-testes barrier that I bet is disrupted if exposed to EMF.

Dr. Salford is quite outspoken about his work. He has called the use of handheld cell phones “the largest human biological experiment ever.” And he has publicly warned that a whole generation of cell-phone-using teenagers may suffer from mental deficits or Alzheimer’s disease by the time they reach middle age.[3]

What if he’s right and entire populations develop Alzheimer’s disease or an equivalent disorder. Dr Salford and Persson demonstrated that a leaking BBB may be just the ticket: (inter alia, microwaves have been shown, by Persson, Salford, and Brun in 1997 (Wireless Networks 3, 455-461), to cause toxins to pass the blood-brain-barrier into the brain where they may initiate Alzheimer’s disease).


[1] Leif G. Salford et al., “Nerve Cell Damage in Mammalian Brain After Exposure to Microwaves from GSM Mobile Phones,” Environmental Health Perspectives 111, no. 7 (2003): 881–883. (http://educate-yourself.org/cn/wirelessandcellphonedangers05oct07.shtml) 05/19/2012

STATINS THE BOTTOM LINE

June 17, 2012

STATINS THE BOTTOM LINE

I like to provide this information to people when they ask if  Mom or Dad or oneself should be prescribed a statin. My sister just returned from her pediatrician’s office and he suggested they check a serum cholesterol on her daughter who is 9 years old. Yes, that’s right. It appears that the statin industry has already seeped, like a sewage lagoon into a ground-water table, into a new market the kid market. Just when you thought it was safe to go back into the water. I do not know how familiar you are with the side effects of statins but try to imagine robbing a 9 year old of CoQ10 and cholesterol for a lifetime! Statins have been around since the mid-1990’s. In a couple years we will hit the 20 year mark and for some that will be the time they have been on a statin. All I can say is that poor bastard. That’s if they make it that long. What might they look like? So far we see brain impairment, massive increases in polyneuropathy, amnesia, weakness, fatigue, sore muscles, aches and pains, impotence, low stress hormones, inability to manufacture Vit D3. Oh but that’s not an issue right because we all know that sunbathing for even 5 minutes shows a clear and consistent linear association with increased skin cancer. OMG! Run. Where’s the slather I need an SPF of at least 100. (Don’t get me started on Vit D 3 and sunlight and tans because I will really get pissed-I love the sun-next blog)

Don’t forget the exponential rise in heart failure over the last decade-CoQ10 related? Could very well be it has not been ruled out.

In summary what can we say about statins so far? (from my upcoming book)

Overall they provide modest protection to women and men, about 20%, against heart attack and overall mortality only in those who already have heart disease (that’s called secondary prevention).

In contradistinction a Jan 17, 2008 Business Week article states-statins have never been shown to benefit women of any age.

As far as primary prevention goes-and this is where the vast majority of prescriptions are sold-the data do not support their use.

Dr Abramson published an article in the Lancet in 2007. Our analysis suggests that lipid-lowering statins should not be prescribed for true primary prevention in women of any age or for men older than 69 years. High-risk men aged 30-69 years should be advised that about 50 patients need to be treated for 5 years to prevent one event. In our experience, many men presented with this evidence do not choose to take a statin, especially when informed of the potential benefits of lifestyle modification on cardiovascular risk and overall health. This approach, based on the best available evidence in the appropriate population, would lead to statins being used by a much smaller proportion of the overall population than recommended by any of the guidelines.[1]

In another study published in the Archives of Internal Medicine in 2010 a group of researchers set out to find if statins should be prescribed for patients without CVD or previous heart attack but are considered high risk for such events. In other words are statins indicated for primary prevention? They looked at over 65,000 patients in a Meta-analysis of 11 studies.

Conclusion This literature-based meta-analysis did not find evidence for the benefit of statin therapy on all-cause mortality in a high-risk primary prevention set-up.[2]


[2]   Statins and All-Cause Mortality in High-Risk Primary Prevention A Meta-analysis of 11 Randomized Controlled Trials Involving 65 229 Participants Kausik K. Ray, MD, MPhil, FACC, FESC; Arch Intern Med. 2010;170(12):1024-1031.                                                                 

In the end I ha…

June 17, 2012

In the end I have to leave you with a comment from Dr Kirsch in his Epilogue from his book The Emperor’s New Drugs Exploding the Antidepressant Myth.

In 2004 the FDA issued a statement to various drug companies to adopt a don’t ask don’t tell policy when it comes to antidepressants and children. The clinical data clearly show that antidepressants are no better than placebo in treating depressed children. The FDA felt that if this information came to light with the general public it might lead doctors to stop prescribing antidepressants for kids. Imagine that, suggesting exercise and proper nutrition instead.

An FDA spokesperson was reported to have said to a Washington Post reporter “Even if the clinical trials show negative results, it doesn’t mean that the drugs are ineffective.”

Kirsch comments that “the assumption seems to have been that doctors should prescribe medications that have not been shown to work, until it has been proven that they don’t work.”

In summary the entire class of new drugs called the SSRI antidepressants (and by inference similar drugs like the SNRI, SSNRI, and atypical antipsychotics) do not work any better than a placebo. This has been conclusively shown in Dr Kirsch’s new book. Exercise, proper nutrition and cognitive therapy work as good acutely and better than drugs in the long run. SSRI’s are not benign drugs. They are fraught with side effects some of which can be life threatening. They also have been shown to incite murder, suicide and generalized mayhem in a significant number of users. Witness 18 American servicemen commit suicide every day. Patients on these drugs for long periods of time become “spellbound” to use a term coined by Peter Breggin, and never get better. In fact, they tend to worsen developing a chronic, depressive condition called Tardive Dysphoria. For about half of the users it’s almost impossible to stop taking the medication which can lead to profound psychiatric disturbances if withdrawn too quickly. Furthermore, it is often the acceleration or deceleration phase of drug dose adjustment that precipitates intense personality changes and the acts of violence that accompany these changes. A perfect example is Andrea Yates who’ s Haldol dose was stopped and Effexor dose doubled-overnight. This does not include the more subtle personality changes that accompany nearly every person who takes an SSRI which includes the “autism of antidepressants.” The past theories of depression including low serotonin brain levels have been debunked as well. The theory of how antidepressants work no longer fits the theory of depression. Depression itself may not be a disease at all in the same sense we define other diseases. With far safer options available these drugs should be eliminated from the market place or only selectively prescribed. This however may be a pipe dream since they are the second most profitable drugs in pharmaceutical history. Statins (another con job) are the most lucrative.

EVEN FAMOUS DOCTORS GET SNUBBED

June 17, 2012

EVEN FAMOUS DOCTORS GET SNUBBED

(An excerpt from my upcoming book).  Fortunately for my ego and feelings of self worth, at about the same time that this case and Jimmie’s future were circling the drain, I stumbled upon an article Dr Russell Blaylock wrote regarding the problems he had dealing with the attending physicians treating his dying brother in a hospital I think in Mississippi (bear with me I am going by memory on this). Now Dr Blaylock is a truly exceptional physician and brilliant (a term I never use). He is the author of one of my all-time favorite books which I have added to my student suggested reading list Excitotoxins The Taste That Kills. He is author of a few other books, has a monthly newsletter that I prescribe to, and scores of research papers and articles. In other words he deserves respect he put in the time and effort.

Dr Blaylock describes how he was ignored, avoided and insulted by these holier-than-thou physicians when he tried to simply talk to them as one physician to another to find out some details on his brother’s care especially with a certain nutrient they were giving him which, as an excitotoxin, was accelerating his fatal pulmonary condition. Just like in my situation Dr Blaylock must have hit a tender spot-a lack of knowledge on excitotoxins. They would not answer or return his calls as if her were a nutcase. After days of being blackballed, as his brother lies dying, he finally had to convey a meeting through administration with all the attending physicians involved in his brother’s care-all the way to the chief of medicine. The chief turned out to be the most arrogant, sanctimonious physician of them all-claiming that if it’s not printed in one of only three journals he reads then it’s not worth knowing. Hmmm, well you probably know by now that a statement like that is pitiable in its ignorance. Recall all of the Marsha Angell and related articles on the corruption of medical studies by Big Pharma I’ve quoted in this book. That’s the last kind of doctor I ever want touching me or a relative. No question about it and unfortunately Commercial Sick Care breeds them like dirty rags breed mice.

Let me ask you why do so many doctors react like that-like a bad cop? You know with hostility, suspicion, and arrogance? It’s rhetorical, I don’t have the answer. It just seems to me anyway that if you are well trained, have a very good, deep knowledge base-and you feel good about your fund of knowledge-you would be open to new and exciting things. You would instinctively know that the more you learn of medicine’s infinite depths the less you really know and besides you can’t know everything. There will always be new and unusual cures and strangeness in medicine. Just like the newly awarded black belt: you are now truly a beginner because you can finally appreciate how little you actually know in the universe of martial arts.

Unfortunately this isn’t the case in medicine-I guess we call that trait humility which seems lacking in many of our doctors. Blaylock’s story is very touching and sad but it also made me feel a little better knowing that if doctors treated a world famous academic physician and author that way then this is a deeply rooted psychiatric problem within the medical establishment and not just my little Rodney Dangerfield problem of no respect.

Enter your zip code here

June 7, 2012

 FLUORIDE

In the rise of obesity chapter I mention that municipal water levels of fluoride can exceed levels used medically to clinically reduce thyroid output. In fact, thyroids were suppressed using fluoride decades ago before other medications were discovered (Stecher 1960; Waldbott 1978).[1]

 It bears noting that according to the Department of Health and Human Services (1991) fluoride exposure in fluoridated communities is estimated to range from 1.6 to 6.6 mg/day, which is a range that actually overlaps the dose (2.3 – 4.5 mg/day) shown to decrease the functioning of the human thyroid (Galletti & Joyet 1958). This is a remarkable fact, particularly considering the rampant and increasing problem of hypothyroidism in the United States (in 1999, the second most prescribed drug of the year was Synthroid, which is a hormone replacement drug used to treat an underactive thyroid). In Russia, Bachinskii (1985) found a lowering of thyroid function, among otherwise healthy people, at 2.3 ppm fluoride in water.[2]

That’s how effective it can be in decreasing thyroid output. Now add conventional produce soaked in fluoride based pesticides, fluoride toothpaste, general anesthetic gases, mechanically deboned meat, tea and dental treatments and you have a problem, a big one.


[1] Paul Connett, PhD

Professor of Chemistry 50 Reasons to Oppose Fluoridation Updated April 12, 2004 (http://www.fluoridealert.org/)

[2] IBID # 22

Statins and CoQ10 depletion

June 4, 2012

This is a (very) Imagesmall piece of my upcoming book. I am going to periodically add in pieces of my work as I go along. Any comments on references or additions would be helpful.

CoQ 10 depletion
There’s a reason why the other name for CoQ 10 is ubiquinone as in ubiquitous because it’s everywhere in your body er, well, it’s supposed to be unless you are on a statin. Now imagine what that’s like depleting a vital molecule everywhere in your body for the rest of your life! CoQ 10 is critically needed in what is called cellular aerobic respiration which is the main way we use energy. In fact 95% of the body’s energy (ATP) is generated this way.  CoQ 10 is so vital that there is no other molecule that can perform its duties of transferring electrons from complex Icomplex IIcomplex III in the electron transport chain (ETC) within the mitochondria. If we lost this ability we could not utilize oxygen to live. Cyanide owes its lethality to this very property. The organs most dependent on large quantities of CoQ 10 and hence aerobic energy are the heart, liver and kidneys.

Finally CoQ 10 is a potent antioxidant in many cellular systems it is also located within the LDL cholesterol molecule, where it functions to keep LDL from being oxidized.

The second fundamental property of CoQlo involves its antioxidant (free radical scavenging) fimctions (Beyer 1990, Villalba 1997). CoQlo is the only known naturally occurring lipid soluble antioxidant for which the body has enzyme systems capable of regenerating the active reduced ubiquinol form (Ernster 1993) It is also known that CoQ10 levels steadily fall after the age of 40 (Kalen 1989,
Soderberg 1990). .

Need I say more to impress upon you how important it is to maintain adequate levels of CoQ 10? Statins critically reduce the levels of this important molecule and those who are on statins are all part of a massive experiment. What happens when you keep reducing a patient’s CoQ 10 levels for decades? We do not know for sure but a massive rise in congestive heart failure in the last decade may be due at least in part to this.  As a precaution which is backed up by dozens of studies Peter H. Langsjoen, M.D., author of the quote above, suggests that we supplement with 100-200 mg of CoQ 10 per day if on a statin. He also suggested due to overwhelming evidence that the FDA provide a Black Box warning  for all patients that emphasizes the dangers and importance of supplementation with CoQ 10 if you are on a statin.

Impotence and Low Testosterone levels
Information from all of these sources identified fibrates as a source of ED. A substantial number of cases of ED associated with statin usage have been reported to regulatory agencies. Case reports and clinical trial evidence supported the suggestion that statins can also cause ED.
In a new study out of Italy researchers found a correlation with statins and ED: April 16, 2010 — Statin therapy prescribed to lower cholesterol also appears to lower testosterone, according to a new study that evaluated nearly 3,500 men who had erectile dysfunction or ED.
”Current statin therapy is associated with a twofold increased prevalence of hypogonadism,” a condition in which men don’t produce enough testosterone, study author Giovanni Corona, MD, PHD, a researcher at the University of Florence in Italy.
Researchers appear to be stymied by the mechanism suggesting that there is either a correlation between low testosterone (T) and high LDL or the fact that statins can decrease the production of testosterone by critically decreasing the building blocks namely cholesterol. How about both? We often see an increase in serum lipids as a persons T falls in the same way that we see it with hypothyroidism which the study should have checked for as well. Likewise it has been shown that statins can reduce critical hormone levels of both the sex and stress variety.

Statins can apparently interfere with orgasms as well: In “Statins Reduce Orgasm: Results from the UCSD Statins Study” Dr. Beatrice Golomb and colleagues from the University of California-San Diego reported today on their study of 1,067 men and women without heart disease with a LDL cholesterol of 119-190 mg/dL. Overall statins had a negative effect on orgasms, which was statistically significant only for men, and only for Zocor. Dr Golomb was quoted as saying that “it takes a lot of energy to orgasm,” implying that CoQ 10 depletion may be involved.

sorry but my footnote numbers disappeared after copy and paste…..

(https://en.wikipedia.org/wiki/Coenzyme_Q10) 06/03/2012
(http://www.fda.gov/ohrms/dockets/dailys/02/May02/052902/02p-0244-cp00001-02-Exhibit_A-vol1.pdf) 06/04/2012
(http://www.fda.gov/ohrms/dockets/dailys/02/May02/052902/02p-0244-cp00001-02-Exhibit_A-vol1.pdf) 09/04/2012
Rizvi K, Hampson JP and Harvey JN. Do lipid-lowering drugs cause erectile dysfunction? A systematic review. Family Practice 2002; 19: 95–98.
(http://www.webmd.com/erectile-dysfunction/news/20100416/statins_may_lower_testosterone_libido) 06/04/2012
(http://www.beforeyoutakethatpill.com/index.php/2009/03/06/statins-interfere-with-orgasms-live-update-from-aps-in-chicago/) 06/04/2012